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My Resume


Poised to contribute a unique blend of PhD level academic and research experience, alongside executive success in healthcare, biotech and genetics industries. Enthusiastic professional with proven record of research on molecular genetics (Publication 1), molecular biophysics (P2, P3, P4, P7), molecular, genetic, biochemical research (P5, P6), and human genetics (P8, P9, P10, P11, P12); and successful strategy execution in two enterprises (Izmir Genetik and AKSE Genetik) growing into a final EBIDTA of $5M+.


Translational Research, Product Research Development, Integrative Marketing and Sales in Diagnostic Testing. Genotype - Phenotype Correlation, Variant Analysis and Clinical correlation utilizing Exome Sequence data. Molecular Genetic Analysis and Epigenetics – with a special interest in Bioinformatics and Nutrigenetics. Molecular Biology and Genetics with a special interest in bioanalytical, biophysical and computational analysis. Molecular Biophysics, Genetic Screening, Biochemistry and Behavioral Genetics. Neuroeconomics.


CALYX CONSULTING ( – Founder                                   

01/2020 – current

  • Established numerous national and international collaborations in reproductive biology and oncology.

İZMİR GENETİK ( – General Manager                               

06/2016 – current

  • Grew the company from start to a licensed / certified genetics laboratory, performed 20,000+ genetic testing.

  • Established numerous national and international collaborations in reproductive biology and oncology.

  • Managed to grow the marketing team of the company to 10+ marketing agents throughout Turkey.

  • Currently manage 22+ personnel at various levels, achieving a yearly EBITDA of $5M+.


AKSE GENETİK – General Manager                                                                        

10/2015 – current

  • Created and implemented a novel genetic product in exome sequencing, with a special interest in nutrigenetics.

  • Prepared and received funding for 9 research projects in the fields of human molecular genetics and testing.

  • Completed 10 research projects with 4 graduate and 6 undergraduate students and published 7 manuscripts.


PHARMAPLUS GENETİK – Genetics and Business Development Specialist             

06/2014 – 10/2015

  • Managed launch of a medical diagnostic laboratory using Next Generation Sequencing (NGS), NextSeq 500. 

  • Launched the first product of the company; Non-Invasive Prenatal Test (NIPT).


BLACKMORE PARTNERS – Equity Research Intermediate                                    

08/2012 – 05/2014

  • Managed setting up of a genetic laboratory using Next Generation Sequencing (NGS), NextSeq 500. 


Assistant Professor


Faculty of Medicine, Istanbul Altinbas University, Turkey


Post-Doctoral Associate


Dpt. of Biological Sciences, Middle East Technical University, Turkey.




Department of Sciences, Morton College, USA.


Chemistry Laboratory Coordinator


Dpt. Of Chemistry, University of Illinois at Chicago, IL




Department of Business Administration, Wayne State College, Nebraska




Department of Chemistry, University of Illinois at Chicago, Illinois.




Department of Molecular Biology and Genetics, Bilkent University, Turkey.




Department of Molecular Biology and Genetics, Middle East Technical University, Turkey.

Research Experience

AkSe Genetik, İlaç ve Biyoteknoloji Ltd. Şti., Turkey                                                   

2/2015 – current

  • Launched numerous research projects in genetics and molecular biophysics. 

1. Novel biophysical technique aimed for identification of aneuploidies. TUBITAK 1512 TeknoGirişim Support.

2. Identification of genomic alterations in childhood Langerhans cell histocytosis using targeted next-generation sequencing technology for designing a novel diagnostic tumor panel. Submitted as TUBITAK 1003 grant proposal (1.3M TL) with Prof. Dr. Erdener Özer from Dokuz Eylül Üniversity, Faculty of Medicine.

  • Prepared several research projects in submission stage to KOSGEB, TEB and other supporting agencies.

1. Development of a novel DermoCosmetic genetic panel for personalized skincare. Project proposal in preparation with DSE Dermokozmetik Ltd. Şti. and will be submitted to KOSGEB and TEB grant support.

2. Development of a novel technique for accurate and industrial scale sexing of un-incubated eggs in order to avoid undesirable culturing and elimination of male chicks. This project is in preparation for submission to both KOSGEB and GreenPeace with Animal Welfare perspective.


İzmir Genetik Araştırma ve Ticaret Ltd. Şti., Turkey                                                    

10/2015 – current

  • Provided scientific and research-based support to Izmir Genetik management and sales team for introduction and marketing of numerous advanced genetic tests to Turkish market.

  • Formulated several research projects aimed for adaptation of numerous advanced genetic tests to Turkish population. Two projects are being submitted to TUBITAK for support.

  • Performed initial feasibility analysis of advanced genetic tests for Turkish market and successfully handled their implementation and initiation. 


İstanbul Altınbaş University, Department of Medical Biochemistry, Turkey

01/2017 – 01/2019

  • Taught Molecular and Cellular Medical Sciences I, II, III and IV.

  • Launched 3 courses; Molecular Genetic Counseling, Nutrigenomics, Translational Research in Healthsciences.

  • Prepared and participated numerous research projects in molecular genetics and biophysics. 

  • Successfully completed graduate training of three scientists and published their projects.

1. Development of a novel therapeutical technique aimed for identification of aneuploidies for prenatal diagnosis. TUBITAK 1512 TeknoGirişim Support (150,000 TL).

2. Utilization of molecular biophysical techniques for clinical evaluation of breast milk samples.

3. Next generation genetic tests and their use in translational science for personalized and precision medicine.


Department of Biological Sciences, Middle East Technical University, Turkey

10/2014 – 02/2017

  • Launched numerous research projects in molecular biophysics and biochemistry. 

  1. Characterization of Alzheimer's disease and mild cognitive impairment from body fluids for differential diagnosis.  Collaborative project of METU-Biological Science Department and Neurology Department of İzmir Tepecik Training and Research Hospital. 

  2. Therapeutic effects of γ-tocotrienol on liver carcinogenesis and physiology. TUBITAK 2232 fellowship project (March- 2015-March 2017). 

  3. Understanding the molecular effects of novel antidepressant agomelatine on cellular membranes.

  • Handled collaborative projects involving the application of spectroscopic and calorimetric techniques in wide range of scientific research proposals, such as; molecular neurobiology and phylogenic research in botany.


Pharmaplus Healthcare and Medical Research and Development, Turkey

06/2015 – 10/2015

•  Built and managed a fully functional Next-Generation Sequencing genetic analysis laboratory designed to work in the field of non-invasive prenatal testing (NIPT). 

•  Launched several research projects in genetics and biochemistry of human disease conditions.

1. Validation and Improvement of a novel Non-Invasive Prenatal Test (NIPT) using Next Generation Sequencing (including fetal fraction determination and development of a development of a point-of-care personalized sample collection kit). Submitted to TUBITAK 1003 call and accepted for the second level application.

2. Development of a novel panel for the determination of major pathological genetic disorders.  Being prepared as a TUBITAK 1507 project proposal in collaboration with Prof. Erdener Ozer, Dokuz Eylül University.

3. Utilization of Next Generation System for development of Preimplantation Genetics Screening kit using NextSeq 500. Being prepared as a TUBITAK 3001 project proposal.


University of Illinois at Chicago, Chicago                                                                   

07/2004 – 05/2011

  • Successfully completed several research projects in neuroscience, bioanalytical chemistry, biochemistry and biophysical chemistry meeting all goals and timelines, including;

  1. Genetic screening of brain cDNA library for interacting protein partners in Alzheimer's Disease. 

  2. Quantitative analysis of 32 novel brain proteins and their interaction with neuronal cytoskeleton.

  3. Genetic engineering and characterization of 14 human brain proteins that interact with SpbII. 

  4. Comparative analysis of Genetic & Biophysical techniques with directed mutagenesis techniques.

  5. Isotermal Titration Calorimetric analysis for mutational effects (G46) on spectrin tetramerization.


Department of Molecular Biology and Genetics, Bilkent University, Turkey 

08/2001 – 05/2004

  • Molecular genetics analysis of determinants of human cancers and neurodegenerative diseases. 

  • Elucidation of RTT mutations and their involvement in the Neurodegenerative RETT Syndrome.

  • Utilized Radioactive and SSCP-based techniques for the routine analysis of mutation detection. 

  • Studied impacts of CHEK2, RNASEL variants and X-chromosome inactivation. 


1.    Sevinc A., et al. Lack of association between RNASEL Arg462Gln variant and the risk of breast cancer. Anticancer Res. 24 (2004) 2547-2549. 

2.    Sevinc A., and Fung L. W.-M. Mutational effects on brain spectrin tetramerization. FEBS Lett. 273 (2006) 239. 


3.    Kang J., Song Y., Sevinc A., Fung L. W.-M. Important residue (G46) in erythroid spectrin tetramer formation. Cell. Mol. Biol. Lett. 15 (2010) 46-54.


4.    Sevinc A., Witek M., and Fung L. W.-M. Yeast two-hybrid and ITC studies of alpha and beta spectrin interaction at the tetramerization site. Cell. Mol. Biol. Lett. 16 (2011) 452-461. 


5.    Sevinc A., and Fung L. W.-M. Non-erythroid beta spectrin interacting proteins and their effects on spectrin tetramerization. Cell. Mol. Biol. Lett. 16 (2011) 595-606. 


6.    Sevinc, A., Yonar, D., Severcan, F. Investigation of neurodegenerative diseases from body fluid samples using Fourier transform infrared (FTIR) spectroscopy.  Biomedical Spectroscopy and Imaging 4 (2015) 341-357. 


7.    Sevinc, A., et al. Possible therapeutic effects of Gamma-Tocotrienol Conjugation Therapy with Doxorubicin on Hepatocellular Carcinoma Cell Line HEPG2. Biophysical Journal 113(3) (2017) 280a. 


8.    Aghayeva, N., Belian, A., Yaylım, İ., Turan, S., and Sevinc, A. Lack of association between the occurrence of ectopic pregnancy and variations in the TGFβI and E-Cadherin genes. MOJ Proteomics & Bioinformatics 8(1) (2019) 1-5.


9.    Ozer, E., Sevinc, A., Ince D., Yuzuguldu, R., and Olgun, N. BRAF V600E Mutation: A Significant Biomarker for Prediction of Disease Relapse in Pediatric Langerhans Cell Histiocytosis. Pediatric and Developmental Biology (2019) 1-7.


10.    Eralp, T.N., Celik, S., and Sevinc, A. A novel genetic interplay in Marfan syndrome: a brief review of literature and presentation of a case. MOJ Proteomics & Bioinformatics 10(1) (2020).


11.    Eralp, T.N. and Sevinc, A. Gamma-tocotrienol therapy and its apoptotic effects on different cancer types. Recent Advances in Molecular Biology and Biochemistry 25 (2023).


12.    Eralp, T.N., Sevinc, A., and Mansuroglu, B. Combination therapy application of Abemaciclib with Doxorubicin in triple negative breast cancer cell line MDA-MB-231. Cellular and Molecular Biology 70(2) (2024) 169-177.

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